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  Indian J Med Microbiol
 

Figure 3: Venous patches lose COUP-TFII and gain notch-4 and dll-4 expression the rat aorta. (a-c) Bar graphs show relative mRNA transcript expression of dll-4, notch-4, and COUP-TFII after direct suture (a), jugular vein patch (b), or carotid artery patch (c), day 0 and day 14; *P < 0.05; (t-test); n = 3. (d) Representative photomicrographs show native aorta, native jugular vein, day 0, and neointima of direct suture, jugular vein patch, or carotid artery patch, day 14. Upper row, anti-dll-4; second row, anti-notch-4; third row, anti-COUP-TF II; scale bar, 100 μm; L, lumen; yellow arrows show the positive cells; n = 3–5. (e-g) Bar graphs show percentages of notch-4 positive (e), dll-4 positive (f), or COUP-TF II-positive (g) cells among endothelial cells, day 14; *P < 0.005 (ANOVA); n = 3–5

Figure 3: Venous patches lose COUP-TFII and gain notch-4 and dll-4 expression the rat aorta. (a-c) Bar graphs show relative mRNA transcript expression of dll-4, notch-4, and COUP-TFII after direct suture (a), jugular vein patch (b), or carotid artery patch (c), day 0 and day 14; *<i>P</i> < 0.05; (<i>t</i>-test); <i>n</i> = 3. (d) Representative photomicrographs show native aorta, native jugular vein, day 0, and neointima of direct suture, jugular vein patch, or carotid artery patch, day 14. Upper row, anti-dll-4; second row, anti-notch-4; third row, anti-COUP-TF II; scale bar, 100 μm; L, lumen; yellow arrows show the positive cells; <i>n</i> = 3–5. (e-g) Bar graphs show percentages of notch-4 positive (e), dll-4 positive (f), or COUP-TF II-positive (g) cells among endothelial cells, day 14; *<i>P</i> < 0.005 (ANOVA); <i>n</i> = 3–5